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CELAM

Centre for Ethics, Law and Mental Health conducts, supports and disseminates research about mental disorders, aggressive behaviour and moral and legal responsibility in an inter-disciplinary framework. The centre is a collaboration between University of Gothenburg, The National Board of Forensic Medicine, Swedish Prison and Probation Service, and The Forensic Psychiatric Clinic, Sahlgrenska University Hospital.

The aims of the Centre are to:

  • stimulate inter-disciplinary research within the area
  • support national and international scientific exchange
  • offer education and tutoring for graduate and post-graduate students
  • interact with the governmental organisations responsible for adolescent and adult criminal offenders with mental health problems
  • inform the public about up-to-date research within the area

Research Output - Recently published

  • Setareh Alabaf; Christopher Gillberg; Sebastian Lundström; Paul Lichtenstein; Nóra Kerekes; Maria Råstam; Henrik Anckarsäter (2018). 
    Physical health in children with neurodevelopmental disorders. ISSN: 1573-3432, GUP 269775

 

  • Viktoria Johansson; Eva Norén Selinus; Ralf Kuja-Halkola; Sebastian Lundström; Natalie Durbeej; Henrik Anckarsäter; Paul Lichtenstein; Clara Hellner (2018).
    The Quantified Behavioral Test Failed to Differentiate ADHD in Adolescents With Neurodevelopmental Problems. ISSN: 1557-1246, GUP 269328

 

  • Carl Delfin; Peter Andiné; Björn Hofvander; Eva Billstedt; Märta Wallinius (2018).
    Examining Associations Between Psychopathic Traits and Executive Functions in Incarcerated Violent Offenders ISSN: 1664-0640, GUP 269216

 

  • Marie Claire Saunders; Henrik Anckarsäter; Sebastian Lundström; Clara Hellner; Paul Lichtenstein; Nathalie M G Fontaine (2018).
    The Associations between Callous-unemotional Traits and Symptoms of Conduct Problems, Hyperactivity and Emotional Problems: A Study of Adolescent Twins Screened for Neurodevelopmental Problems. ISSN: 1573-2835, GUP 268915

 

  • Margherita Malanchini; Emily Smith-Woolley; Ziada Ayorech; Kaili Rimfeld; Eva Krapohl; Eero Vuoksimaa; Tellervo Korhonen; Meike Bartels; Toos C E M van Beijsterveldt; Richard J Rose; Jaakko Kaprio; Paul Lichtenstein; Dorret I Boomsma; Robert Plomin; Henrik Anckarsäter (2018).
    Aggressive behaviour in childhood and adolescence: the role of smoking during pregnancy, evidence from four twin cohorts in the EU-ACTION consortium. ISSN: 1469-8978, GUP 268914

 

  • Eirini Alexiou; Helle Wijk; G. Ahlquist; Anette Kullgren; Alessio Innocenti (2018).
    Sustainability of a person-centered ward atmosphere and possibility to provide person-centered forensic psychiatric care after facility relocation ISSN: 1752-928X, GUP 268861

 

  • Olof Svensson; Karolina Sörman; Natalie Durbeej; Paul Lichtenstein; Henrik Anckarsäter; Nora Kerekes; Thomas Nilsson (2018).
    Associations Between Conduct Disorder, Neurodevelopmental Problems and Psychopathic Personality Traits in a Swedish Twin Youth Population ISSN: 0882-2689, GUP 268724

 

  • Henrik Bergman; Thomas Nilsson; Peter Andiné; Alessio Degl'Innocenti; Roland Thomeé; Annelie Gutke (2018).
    Physical performance and physical activity of patients under compulsory forensic psychiatric inpatient care. ISSN: 1532-5040, GUP 268575

 

  • O. Pain; F. Dudbridge; A. G. Cardno; D. Freeman; Y. Lu; Sebastian Lundström; P. Lichtenstein; A. Ronald (2018).
    Genome-wide analysis of adolescent psychotic-like experiences shows genetic overlap with psychiatric disorders ISSN: 1552-4841, GUP 268555

 

  • Nora Kerekes; Susanne Apelqvist; Cecilia Fielding; Henrik Anckarsäter; Thomas Nilsson (2018).
    The Prison Adjusted Measure of Aggression (PAMA): Psychometric characteristics of a new tool measuring change in aggressive behaviors in correctional settings ISSN: 01651781, GUP 267291

 

  • Olof Arvidsson; Christopher Gillberg; Paul Lichtenstein; Sebastian Lundström (2018).
    Secular changes in the symptom level of clinically diagnosed autism. ISSN: 1469-7610, GUP 267278

 

  • Mina Rydell; Sebastian Lundström; Christopher Gillberg; Paul Lichtenstein; Henrik Larsson (2018).
    Has the attention deficit hyperactivity disorder phenotype become more common in children between 2004 and 2014? Trends over 10 years from a Swedish general population sample. ISSN: 1469-7610, GUP 267275
     

More

Topical Links

  • Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis
    Article in The Lancet Psychiatry 15 February 2017

 

  • Association Between Prescription of Major Psychotropic Medications and Violent Reoffending After Prison Release
    Question:  Is the use of psychotropic medications associated with a lower risk of reoffending for violent crime among released prisoners?
    Findings:  In this cohort study of 22 275 released prisoners, 3 classes of psychotropic medications (antipsychotics, psychostimulants, and medications used for addictive disorders) were associated with statistically significant hazard ratios (0.58, 0.62, and 0.48, respectively) of violent reoffending.
    Meaning:  Evidence-based provision of psychotropic medications to released prisoners was associated with lower risk of reoffending.
    Article in JAMA. 2016;316(17):1798-1807.

 

  • Managing Ethical Challenges to Mental Health Research in Post-Conflict Settings
    Article in Developing World Bioethics April -16
     
  • Genetic background of extreme violent behavior
    In developed countries, the majority of all violent crime is committed by a small group of antisocial recidivistic offenders, but no genes have been shown to contribute to recidivistic violent offending or severe violent behavior, such as homicide.
    Article in Molecular Psychiatry nr. 20 -15
     
  • Cortical and Subcortical Gray Matter Volume in Youths With Conduct Problems
    Article in JAMA Psychiatry. 2016;73(1):64-72

     

More Articles and Links 

Postgraduate studies

We have an extensive research education program, consisting of master/speciality theses, PhD theses and post-doc periods. Mostly, research students are clinicians (medical doctors, psychologists, social workers, physiotherapists or nurses) in the various services collaborating with us, but we also have externally recruited students as often as possible, including non-clinicians. During the last decade, we have had at least one PhD per year, all of whom have either gone on to pursue research in various positions or left for retirement having reached the stipulated age of retirement in Sweden. Our post-docs have generally continued careers in science, most of whom are today full professors or docents/readers. All are presented on this web-page.

Cotents of interest

One of the largest studies of somatic disorders in neurodevelopmental problems presented

New study in 28058 Swedish 9- and 12-year-old twins showed significant overrepresentations of epilepsy, migraine, asthma, cancer, lactose, celiac disease, diarrhea, constipation and enuresis/encopresis in children with autism spectrum disorders (ASDs), attention-deficit/hyperactivity disorder, learning disorder or combinations thereof. It is one of the largest studies of somatic disorders in neurodevelopmental problems presented, and was published in Journal of Autism and Developmental Disorders. CELAM has been one of the initiating groups behind the study and the development of the telephone interview used to assess the neurodevelopmental problems. The study is a collaboration with the Gillberg Neuropsychiatry Centre at the University of Gothenburg, University West and Karolinska Institutet. The first author, Dr Steareh Alabaf, took part in the amanuensis program at the Sahlgren’s Academy and was hosted by CELAM while doing the study.
GUP 269775

Associations Between Conduct Disorder, Neurodevelopmental Problems and Psychopathic Personality Traits in a Swedish Twin Youth Population

Olof Svensson; Karolina Sörman; Natalie Durbeej; Paul Lichtenstein; Henrik Anckarsäter; Nora Kerekes; Thomas Nilsson (2018). ISSN: 0882-2689, GUP 268724
 

Fetal and postnatal metal dysregulation in autism

"Genetic and environmental factors contribute to the etiologies of autism spectrum disorder (ASD), but evidence of specific environmental exposures and susceptibility windows is limited. Here we study monozygotic and dizygotic twins discordant for ASD to test whether fetal and postnatal metal dysregulation increases ASD risk. Using validated tooth-matrix biomarkers, we estimate pre- and post-natal exposure profiles of essential and toxic elements. Significant divergences are apparent in metal uptake between ASD cases and their control siblings, but only during discrete developmental periods. Cases have reduced uptake of essential elements manganese and zinc, and higher uptake of the neurotoxin lead. Manganese and lead are also correlated with ASD severity and autistic traits. Our study suggests that metal toxicant uptake and essential element deficiency during specific developmental windows increases ASD risk and severity, supporting the hypothesis of systemic elemental dysregulation in ASD. Independent replication in population-based studies is needed to extend these findings."

Artikel i: NATURE COMMUNICATIONS 1 juni 2017
| 8:15493 | DOI: 10.1038/ncomms15493 |www.nature.com/naturecommunications

 

Calendar for CELAM

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Page Manager: Stefan Axelsson|Last update: 1/23/2018
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